Assembly of spirooxindole derivatives via organocatalytic iminium-enamine cascade reactions.
نویسندگان
چکیده
The assembly of complex spirocyclopentaneoxindoles via a novel organocatalytic iminium-enamine cascade process is reported. Reactions between 3-substituted oxindoles and α,β-unsaturated aldehydes catalyzed by second generation prolinol ethers provided the desired products in high yield with excellent levels of enantioselectivity in a single step.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 14 23 شماره
صفحات -
تاریخ انتشار 2012